Karin Lundengård

Karin Lundengård is doing her PhD at CMIV where she is looking at the activity of the brain together with her main supervisor Maria Engström. When the neurons talk to each other they generate electrical signals and this requires energy. To cover the increased need of energy, the brain increases the blood supply, transporting more glucose and oxygen to the active part of the brain. But how does the neurons tell the blood vessels that more energy is needed? The underlying mechanism is called the neurovascular coupling and there are several hypotheses about how it actually works. By making computer models of these different hypotheses we can test them and gain an even better understanding of the brain.

Earlier models that Karin has worked on:
- The Gs- Gi signaling pathway of cardiac beta-adrenoceptors in order to investigate why adult hearts desensitize upon forceful stimulation of beta agonists (find her MSc thesis here).
- How calcium moves in the postsynaptic cell and how this effects facilitation of neuronal signalling (oral presentation at SBMC2012).

MSc in physiology and molecular genetics, BSc with a major in biology and a minor in mathematics (thesis on constructing pseudodata as control when measuring the baroreflex) from Linköping University