Schedule and Speaker List
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MONDAY, DECEMBER 5
Morning Session: Hierarchical modelling (chaired by Jan Brugård, Hiroaki Kitano),
Room: Berzelius-salen
09.00-09.15 Welcome registration
09.15-09.30 Gunnar Cedersund*, Welcome, presentation of workshop
09.30-10.30 Mikael Benson* (MD), IKE, Linköping, UPDATED TIME
Integrated clinical, genomic, network and functional studies to find diagnostic markers for personalized medication.
10.30-11.00 Coffee
11.00-11.20 Peter Fritzson*, IDA, Linköping,
Introduction to Modelica modeling and the OpenModelica and MathModelica tools
11.20-11.40 Elin Nyman*, IKE, Linköping,
Multi-level modeling of type 2 diabetes
11.40-12.00 Matts Karlsson*, IEI, Linköping,
Hierarchical modeling of heart bio-mechanics
12.00-12.20 Marek Mateják*, Pavol Privitzer*, Jiří Kofránek (I), Creative Connections, Czech Republic.
HumMod - a large hierarchical model of integrative human physiology.
12.30-14.00 Lunch
Afternoon Session: Decision-support and clinical practice (chaired by José Pena, Mikael Benson)
Room: IMT1
14.00-15.00 Hiroaki Kitano*, Tokyo/Linköping, via Skype, UPDATED TIME
Systems biology and its application to drug discovery
15.00-15.30 Dirk Repsilber*, Leibniz, Germany.
Screening for molecular signatures in heterogeneous tissue and in pooled samples
15.30-16.00 Coffee
16.00-16.30 Ljijana Majnarić*, Croatia
Possibilities of a systems biology approach in managing simple, clinical parameters
16.30-17.00 Peter Lucas* (MD), Radboud University, The Netherlands
Bayesian Network Modelling for Clinical Decision Making in Liver Disease
17.00-17.30 Agnieszka Onisko*, Pittsburgh, USA, via Skype
Bayesian Modelling for Clinical Decision Support when Screening for Cervical Cancer.
17.30-18.00 Discussion
20.00 Dinner
TUESDAY, DECEMBER 6
Morning Session Diabetes (chaired by Peter Strålfors, Gunnar Cedersund)
Room: IMT1
09.00-09.15 Gunnar Cedersund*, Introduction to day 2
09.15-09.45 Peter Strålfors*, IKE, Linköping
Integration of experiments and mathematical modeling to adipocyte insulin signaling and whole-body glucose homeostasis
09.45-10.15 Matthias König*/Hergo Holzhütter, Berlin, Germany, via Skype
A mathematical model and module for liver metabolism
10.15-10.30 Discussion
10.30-11.00 Coffee
11.00-11.30 Folke Sjöberg*, MD, IKE, Linköping
Microdialysis to investigate metabolic disorders including in critical care
11.30-12.00 Maria Kjelsson*/Mats Karlsson, Uppsala, Sweden
Pharmacokinetic and pharmacodynamic modelling of type 2 diabetes: clinical and pharmaceutical perspectives
12.00-12.30 Morten Gram Pedersen*, University of Padua
Multiscale modeling of insulin secretion
12.30-14.00 Lunch
14.00-14.20 Fredrik Nyström*, MD, IMH, Linköping
Clinical studies on diabetes and cardiovascular complications at the Linköping University Hospital
14.20-14.40 Ferdinand Stückler*, Munich, Germany,
Analysis and modeling of metabolomics data in human cohort and challenging studies
14.40-15.00 Martin Adiels*/Jan Borén (MD), Gothenburg,
Measuring lipid metabolism in vivo: Heterogeneity of hypertriglyceridaemia
15.00-15.30 Discussion: possible joint future major clinical studies?
15.30-16.00 Coffee
Afternoon Session: Heart including atherosclerosis (chaired by Toste Länne, Hiroaki Kitano)
Room: IMT1
16.00-16.20 Hiroaki Kitano*, Tokyo/Linköping
Overview of HD-physiology network
16.20-16.40 Alfredo Hernandez*, INSERM, Rennes, France
Overview of multi-formalism modeling of the cardiovascular system : applications to personalized heart failure therapy
16.40-17.00 Fredrik Elinder*, IKE, Linköping
Electrophysiological cell biology and modeling of the heart
17.00-17.20 Karin Lundengård*/Jordi Altimiras*, IFM, Linköping
Beta-receptor de-sensitization understood using mathematical modeling
17.20-17.40 Toste Länne*(MD, IMH), Linköping,
Modelling and clinical studies of atherosclerosis
17.40-18.15 Discussion: Towards a multi-level model for type 2 diabetes, and its cardiovascular complications?
20 Dinner
WEDNESDAY, DECEMBER 7
Morning Session: Liver diseases (chaired by Mikael Forsgren, Olof Dahlqvist Leinhard)
Room: Wrannesalen CMIV
PLEASE NOTICE THE CHANGE OF ROOM FROM IMT1 TO WRANNESALEN AT CMIV
09.00-09.15 Olof Dahlqvist Leinhard*, CMIV, Linköping, "Introduction to Day 3"
09.15-10.00 Adriano Henney*, Germany
The Virtual Liver network
10.00-10.15 Discussion
10.15-10.45 Coffee)
10.45-11.05 Olof Dahlqvist Leinhard*, CMIV, Linköping
Non-Invasive Liver Biopsy (NILB) I
11.05-11.25 Bengt Norén* (MD), CMIV, UHL, Linköping
Non-Invasive Liver Biopsy (NILB) II
11.25-11.45 Mikael Forsgren*, CMIV, UHL, Linköping
Towards deterministic and Bayesian based models as diagnostic tools
11.45-12.00 Discussion
12.00-13.30 Lunch
13.30-14.15 Jose Ulloa*, AstraZeneca, Stockport, UK
Evaluation of DCEMRI as a Biomarker of Hepatic Transporters Interactions
14.15-14.30 Discussion
14.30-15.00 Marek J Druzdzel*, Pittsburgh, USA, via Skype
Bayesian modeling for clinical decision support when diagnosing diffuse liver disease
15.00-16.00 Coffee and Discussion