Elin Nyman

I use mathematical modeling to get maximal information from data with the goal to get a new understanding of human disease. My research deals with questions related to obesity, diabetes, and cardiovascular disease.

My research focuses on type 2-diabetes and obesity. I study for example the mechanisms of insulin signaling and insulin resistance and the browning of white adipocytes using mathematical modeling. I am also interested in how to combine modeling with large-scale data to better understand the origin to diseases.

The main focus of my research has been the insulin response in human adipocytes, and especially what goes wrong in this response in individuals with type 2 diabetes. My work has resulted in a series of papers unravelling mechanisms of insulin signaling and insulin resistance in type 2 diabetes using mathematical models. I have also analyzed the effect of a potentially anti-diabetic drug combining mechanistic knowledge from the drug effects in cellular studies with the drug effects in clinical studies. This project was a collaboration with the external financiers Wolfram MathCore, MedImmune and AstraZeneca.

Here is a link to my publications.